SYN-AKE Peptide – Mizon S-venom Wrinkle Tox Cream

Syn-ake is supposed to be the “botox in a bottle” solution.  It’s an anti-wrinkle chemical, a synthetic protein fragment that is meant to replicate part of the venom of the Malaysian Temple Viper.  It’s been found to work similar to botox – like how botox paralyzes the muscles that cause expression lines.

Technical details:

Dipeptide Diaminobutyroyl:  Active compound is based on a synthetic tripeptide that mimics the effect of Waglerin 1, found in the venom of the Temple Viper. The activity of snake peptide reduces the contraction frequency of muscle cells on the face, thereby decreasing the appearance of expression lines. In vivo testing showed an impressive reduction of over 50% in wrinkle size after 28 days. Does not contain preservatives. Clear liquid, no odor. pH value 4.5 – 5.5. Easily water-soluble. CAS# 794590-34-4, 883558-32-5, 56-81-5.

Has been found in clinical studies to reduce the appearance of wrinkles and expression lines due to reduction of contraction frequency. Best added to skin serums and creams to target wrinkles around eyes, mouth and forehead.

The Purchase:

This was what I bought:

http://www.amazon.com/Mizon-S-venom-Wrinkle-Cream-Syn-ake4%25/dp/B00HKEY7Q2/ref=sr_1_9?s=beauty&ie=UTF8&qid=1399417947&sr=1-9&keywords=syn-ake

 IMG_2896 IMG_2901-001

I have some fine lines, and I guess I’m pretty obviously obsessed with getting rid of them.

Mizon products are pretty high quality, have good reviews, and my skin seems to like them.  This one is about $30 on Amazon (shipped from Korea) which at 50ml isn’t cheap, but it’s not as high priced as some others I found.

Use:

I used this daily, applying pretty liberally (I have dry skin so I can put on a pretty thick layer of moisturizer) over my C-Serum, and under my sunscreen.  The instructions say to give it some time before putting anything over top, so I waited about 10 mins before adding the sunscreen.

Texture:

This is a pretty greasy feeling moisturizer, but it layers well under sunscreen without pilling.  In the 10 min wait time it didn’t absorb all the way in.

Once applied, it doesn’t seem to relax or paralyze anything…

My fine lines before:

IMG_2805-001

This photo is 6 months old.  From when I started with the sny-ake.

Yep.  Definitely there.  This is with the syn-ake on it, that’s why I look SO SHINY.  I cover all this with makeup.

Right after application, I wasn’t able to see any real difference.  It’s supposed to be able to relax the lines that come from expression…. but my expressions weren’t hindered in the least, so I don’t think it’s doing what it’s supposed to.

My Fine Lines Now:

photo 2 (7)-001

Harsh Lighting

I can still see them, the 11s are alive and well.

Verdict:

I think this product is an interesting gimmick, but I don’t see enough of a difference to continue its use.  If I like the product as a moisturizer more, I’d probably keep using it, just in case it’s doing some kind of work behind the scenes, but as it is, I’m not going to keep using this one.

Just spring for botox, for actual botox effect.

References:

http://www.makingcosmetics.com/msds1/msds-snake-peptide.pdf

http://www.makingcosmetics.com/fact-sheets/fact-sheet-snake-peptide.pdf

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2923951/

http://www.cosdna.com/eng/cosmetic_bc4c89320.html

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